Supplemental Figure S1 presents the corresponding Manhattan plot showing the p-value (−log10 p) of each SNP analyzed in the model adjusted for sex, age, diabetes and BMI. Supplemental Figure S2 shows the corresponding Q-Q plot. Table 5 shows more detailed information on the top-ranked SNPs in the GWAS on plasma adiponectin concentrations adjusted for sex, age, type 2 diabetes and BMI, including the position, the effect (beta regression coefficient), the p-value, the corresponding MAF and the annotated gene. The gene discussed is ADIPOQ; the disease is type 2 diabetes mellitus.