NFE2L2 and hydrops fetalis: Flavones (luteolin and apigenin), flavanones (naringenin and hesperetin) and isoflavones (genistein and daidzein) also appear to reduce oxidative stress and inflammation in HF through similar mechanisms and pathways [125,126,127,128,129,130,131,132,133], by mediating Nrf2 and decreasing inflammatory signaling.