The studies employed mice, rats, or rabbits in various stroke models and the majority of these showed a positive effect regarding infarct volume [42,43,44] (additional source: poster of Veldhuis et al. at the 2002 ISMRM-10th scientific meeting and exhibition in Honolulu, “Delayed treatment with interferon-beta protects against ischemic stroke”, available online) and neurological function regain [44], while one did not show a protective effect and raised safety concerns for the substance [45]. Here, IFNB1 is linked to ischemic stroke.