The following search terms were used: mesothelioma combined with prognostic and predictive biomarker, inflammation, inflammatory markers, C-reactive protein, fibrinogen, neutrophil to lymphocyte ratio, monocyte to lymphocyte ratio, thrombocyte to lymphocyte ratio, neutrophils, leukocytes, monocytes, albumin, Glasgow prognostic score, IL-6, ferritin, tumor microenvironment, tumor infiltrating lymphocytes, tumor associated macrophages/monocytes, PD-L1 and PD1, CTLA-4, immune therapy, and complement system. The gene discussed is CD274; the disease is neoplasm.