We know from our previous studies that several LL37-derived T-cell epitopes bind to HLA-DRB1*1501 and DRB5 [6] or possess “anchor motifs” suitable for HLA-DRB1*0301 allele binding (also linked to SLE, inferred by predictions servers [33]). The gene discussed is HLA-DRB1; the disease is systemic lupus erythematosus.