Six and two HCC biomarkers were abundant in phase II and phase III HCC, respectively, including alpha-2-HS-glycoprotein and apolipoprotein CIII (both ≥0.2%), Ig λ-chain VI region NEWM (≥1.0%), and serum amyloid P component (≥0.3%), which positively correlated with the best OS and RFS. This evidence concerns the gene AHSG and hepatocellular carcinoma.