F8 and COVID-19: Because of the COVID-19-induced damage, endothelium releases several molecules into the blood, including vWF, FVIII, tissue plasminogen activator-1 (t-PA-1) and P-selectin, which are usually stored within secretory organelles called Weibel–Palade bodies (WPB) that participate in platelet adhesion, secondary hemostasis and fibrinolysis [67].