Silber et al. identified miR-124 and miR-137 as downregulated in glioma stem cells and involved in the maintenance of their stemness [43], and Kefas et al. defined miR-7 as a tumor suppressor in GBM, regulating cell viability and invasiveness of cancer cells by targeting the Epidermal Growth Factor Receptor (EGFR) [44]. This evidence concerns the gene EGFR and central nervous system cancer.