HSP90B2P and atrial fibrillation: Drosophila, cardiomyocyte, and canine models of AF show that HSP-inducing compounds such as geranylgeranylacetone and their derivatives can prevent proteostasis and cardiac remodeling, thus attenuating AF progression (Brundel et al. 2006; Zhang et al. 2011; Hoogstra-Berends et al. 2012).