CD40LG and systemic lupus erythematosus: IgG and/or IgA and IgM (immunoglobulin G, A and M) antibodies that hydrolyse DNA, RNA, adenosine triphosphate (ATP), polysaccharides, peptides and proteins were found in the blood of patients for various autoimmune pathologies (AIPs), including systemic lupus erythematosus (SLE), multiple sclerosis (MS), Hashimoto's thyroiditis, polyarthritis, lymphoproliferative diseases, polyneuritis and malignant tumours, as well as for three viral diseases—viral hepatitis, tick‐borne encephalitis and human immunodeficiency (Refs.