KLK3 and posterior cortical atrophy: This meta-analysis included 22 studies which reported biopsy at ≥2 years post-EBRT as an endpoint or study observation and utilised EBRT alone or in combination with androgen deprivation therapy (ADT) as primary treatment for low to intermediate risk PCa (PSA ≤ 20 ng/ml, Gleason score  ≤ 7, clinical stage ≤ T2b).