Mice that underwent treatment with anti-neu antibody and 558 had a significantly higher percent of NK cells (P < 0.05, Fig. 7A), as well as NKG2D + NK cells (P < 0.05, Fig. 7C) within the tumor—a receptor on NK cells that has been shown to be one of the key triggers in their activation status25. Here, KLRK1 is linked to neoplasm.