SENP3 and hepatocellular carcinoma: Cox regression analysis evaluated the prognostic power of the three genes (Table 6) and showed that SENP3 as a single gene, the combination of two genes (ARID1A and SENP3; CSMD1 and SENP3), and the combination of three genes (ARID1A, CSMD1, and SENP3) could be used as prognostic biomarkers for HCC (P < 0.05, Table 6 and Figure 5).