While excess IL-10 production early during infection may be detrimental during KPPR1 pneumonia in mice, cells that resembled M-MDSCs, or MDSC-like cells, were recruited to the lungs later during infection (i.e., 72 h), and appeared to play a beneficial role by mediating the clearance of apoptotic neutrophils by efferocytosis (104). This evidence concerns the gene IL10 and infection.