DROSHA and Nephroblastoma: Somatic mutations of DROSHA have been shown to be frequent and underlie high risk of Wilms' tumors (Spreafico et al., 2016; Torrezan et al., 2014; Wegert et al., 2015), and DROSHA depletion has been reported to be implicated in the promotion of a migratory phenotype in lung cancer cells (Frixa et al., 2017).