KCNQ2 and Epileptic encephalopathy: Therefore, we tested this hypothesis by searching for CNV variome differences among the four family members of a complex case of a child, as test case, that presented a developmental and epileptic encephalopathy of neonatal onset that has a novel KCNQ2 mutation resulting from a partial KCNQ2 exon 7 duplication that impairs its inhibitory signal [17] and to determine if the proband has a CNV pattern associated to neuronal functions.