MYO5B and hepatocellular carcinoma: Moreover, the depletion of myosin Vb from mouse livers, cultured hepatoma cell lines or induced pluripotent stem cell (iPSC)-derived hepatocytes, or the expression of nonsense MYO5B mutants in these cells, did not cause the mislocalization of bile canalicular transporter proteins ABCC2 and anoctamin-6 in the steady state [74].