IL1B and colitis: These data remain in agreement with the study by Sideri et al. [44], in which a pronounced relationship between HFD and exacerbated intestinal damage in mice with TNBS colitis was demonstrated followed by the increased expression of proinflammatory biomarkers such as IL-1β, TNF-α and monocyte chemoattractant protein 1 in mesenteric adipose and intestinal tissues.