In order to determine the expression levels of HLA-I/APM components in OSCC, protein expression of HLA-I HC, β2-m and the APM molecules TAP1, TAP2, LMP2 and LMP10 were analyzed by IHC of formalin-fixed, paraffin-embedded (FFPE) tumor lesions [35]. The gene discussed is B2M; the disease is neoplasm.