In turn, the studies of Ohmori et al. suggest that only TNF-α, the levels of which were negatively correlated with skeletal-muscle index (SMI) and SDS-soluble myosin light chain 1 (SDS-MYL1), is a good serum muscle-atrophy marker in CRC-associated cachexia [67]. The gene discussed is MYL1; the disease is colorectal carcinoma.