Since the functional basis of PPI is regulated by interactions between various structures, including hippocampal and cerebral inputs [108,109], as well as by dopamine [108,110] and serotonin transmission [111,112], and CX3CL1 participates in the regulation of these neurotransmitters, the changes in this signalling observed between the offspring groups (MIAPPI-low and MIAPPI-high) may be reflected by differences in behavioural schizophrenia-like patterns. The gene discussed is CX3CL1; the disease is schizophrenia.