CX3CL1 and schizophrenia: In this proof-of-concept study, we explored the hypothesis that acute treatment with Poly I:C in the late period of gestation modulates the CX3CL1-CX3CR1 and/or CD200-CD200R axes and microglial trajectory and entails schizophrenia-like deficits in adult male offspring of Sprague-Dawley rats.