Currently known mutations in FLNC gene are mapped to the protein structure and correlated to the phenotype of various skeletal muscle myopathies (MFM, distal myopathy (DM) and limb-girdle muscular dystrophy (LGMD)) on the left, whereas correlation with various forms of human cardiomyopathy (ABiMVPS, DCM, HCM, ARVC, RCM) phenotypes are displayed on the right (adapted from Mao et al. [7]). This evidence concerns the gene FLNC and cardiomyopathy, familial restrictive, 1.