At sarcomeric z-discs, filamin C interacts with various proteins partially linked to inherited cardiomyopathies like calsarcins (Involved in HCM [9,10,11]), myopalladin (linked to RCM [12]), cypher (linked to ARVC and DCM [13]), actin (linked to DCM [14]), myotilin, myopodin, and others. This evidence concerns the gene LDB3 and familial dilated cardiomyopathy.