CCL11 and asthma: We show that eotaxin expression is significantly increased in cultured ASM derived from patients with moderate asthma compared with that derived from patients without asthma, and this appeared to be associated with the severity of asthmatic disease in the tissues biopsied and with which ASM bundles were dissected (P < 0.05; Figure 6K), as has been seen by others in the secretions of asthmatic airways (44–46).