Interestingly, a study showed that CSe+ infants with high hereditary allergy risk, but who did not develop IgE allergic disease and IgE eczema at two years, consumed breast milk with higher levels of 2’-FL, suggesting a protective role of α1–2 fucosylated HMOs in the manifestation of atopy [43]. This evidence concerns the gene IGHE and Eczematoid dermatitis.