Cytotoxicity of AMP-001-003 was investigated in a variety of cancer cells including TNBC cells (MDA-MB-231, 4T1 ER, PR and HER2 negative), breast cancer cells (MCF-7, Luminal, ER positive), gastric cancer cells (MGC-803, SGC-7091), lung (A549), normal breast epithelial cells (MCF-10A), bone marrow cells (MSC-001F) and induced pluripotent stem cells derived (iPSc) cardiomyocytes are shown in Table 1. Here, ESR1 is linked to cancer.