Eight genes (B4GALT7, CHST12, GALE, IL13RA1, SPAG4, STC1, TGFBI, and TPBG) were significantly upregulated in GBM samples, and two genes (G6PC2 and LDHB) were significantly upregulated in LGG samples (p < 0.0001, Figure 2). The gene discussed is SPAG4; the disease is glioblastoma.