Ten glucose metabolism-related biomarker genes (B4GALT7, CHST12, G6PC2, GALE, IL13RA1, LDHB, SPAG4, STC1, TGFBI, and TPBG) were found to be statistically and biologically significant in the discrimination of LGGs from GBM in this study (Table 1). Here, SPAG4 is linked to glioblastoma.