The low expression of CLEC3B was correlated with poor overall survival in HCC, head and neck squamous cell carcinoma, kidney renal clear cell carcinoma (KIRC), lower grade glioma (LGG), lung adenocarcinoma (LUAD), poor disease-free survival in HCC, esophageal carcinoma, KIRC, LGG, pancreatic adenocarcinoma, and thyroid carcinoma (Supplementary Figure 2). Here, CLEC3B is linked to central nervous system cancer.