MBL2 and diabetic kidney disease: Zheng et al. studied 62 kidney biopsies from DKD patients and observed prominent MBL, MBL-associated serine protease 1 (MASP1), and MAC immune-reactivity in tubulointerstitial tissue; by converse, intrarenal C1q deposits did not correlate with disease status, suggesting that the classical pathway of complement activation does not play a dominant role (29).