TGFBR2 and cancer: The currently known genetic alterations associated with CC involve the ErbB-3 (Di et al., 2015; Cancer Genome Atlas Research Network et al., 2017), epidermal growth factor receptor (EGFR) (Wei et al., 2018), Serine/Threonine Kinase 11 (STK11) (Hirose et al., 2020), transforming growth factor-beta receptor 2 (TGFBR2) (Cai et al., 2018), phosphatase and tensin homolog (PTEN) (Nero et al., 2019), etc. Nevertheless, the underlying mechanisms of CC carcinogenesis and progression still remain elusive so far.