In agreement with this, cdG and cdA adducts accumulate in DNA of keratinocytes from NER-deficient xeroderma pigmentosum (XP) complementation group C (XPC) and CSA patients exposed to X-rays and potassium bromate (KBrO3) (D'Errico et al., 2006, 2007), as well as in organs of CSB−/− knockout mice (Wang et al., 2012; Chatgilialoglu et al., 2019). This evidence concerns the gene CDA and xeroderma pigmentosum.