IGHE and cystic fibrosis: According to the 2003 CFF (Cystic Fibrosis Foundation) consensus criteria, classic diagnosis of ABPA comprises clinical deterioration not attributed to other causes, serum IgE >1000 IU/ml, a positive skin prick test or positive specific IgE, antibodies against Af, precipitating or IgG antibodies against Af, and radiological changes that are not treatable by antibiotics.