AFP and intrahepatic cholangiocarcinoma: Multivariate analysis by stepwise regression revealed that T classification of AJCC 8th (HR, 1.204; 95% CI, 1.142–1.270), N (HR, 1.927; 95% CI, 1.655–2.243), ln (CEA) (HR, 1.158; 95% CI, 1.098–1.221), ln (CA19-9) (HR, 1.127; 95% CI, 1.085–1.171), ln (AFP) (HR, 1.057; 95% CI, 1.019–1.096), and ln (PA) (HR, 0.830; 95% CI, 0.714–0.964) were determined to be independent predictors of 3-year OS in ICC patients.