Consistent with the transcriptome data from the TCGA-LIHC cohort, a significantly higher density of CD8+ T cells (median, 46 vs 20 cells/mm2, P < 0.0001), CD20+ B cells (median, 145 vs 133 cells/mm2, P = 0.0475), CD56+ NK cells (median, 10 vs 6.5 cells/mm2, P = 0.0276), and CD68+ macrophages’ (median, 1738 vs 1358 cells/mm2, P < 0.0001) infiltration were found in the non-tumor versus tumor liver comparison in training cohort. Here, NCAM1 is linked to neoplasm.