TP53 and cancer: The GSEA results included: Cancer-related terms (such as epithelial-mesenchymal transition, hedgehog signaling, P53 pathway, and MYC targets V2; metabolism-related annotation (such as oxidative phosphorylation, reactive oxygen species pathway, and glycolysis); immune-related annotation (such as interferon-alpha response and TGF beta signaling) (Figure 6D).