Coinhibition of WEE1 with either radiotherapy or anticancer drugs such as cisplatin, gemcitabin, paclitaxel, or inhibitors of CDC25, ATR, or PARP causes death of breast cancer cells.[15, 16, 17, 18, 19, 20, 21, 22] The rational of these combined treatments is to associate DNA‐damaging therapies together with perturbation of DNA damage checkpoint gatekeepers through WEE1 targeting. Here, WEE1 is linked to breast carcinoma.