MMP2 and glioblastoma: In brief, these results revealed that SynB3‐PVGLIG‐PTX could effectively inhibit the migration and invasion of GBM cells in the presence of MMP‐2 in vitro, and that SynB3‐PVGLIG‐PTX does not exhibit independent antimigratory and anti‐invasive actions without being assisted by the proteolytic effect of MMP‐2.