While NK cells are scarce in the inflamed muscles of patients with anti‐synthetase syndrome, they are greatly expanded in affected lungs and express granzyme B.98The number of circulating NK cells in active anti‐synthetase syndrome patients is comparable to healthy controls, but there is a higher frequency of NK cells expressing granzyme B. These NK cells display a mature CD57hi phenotype but low levels of NKp30 activating receptor.98 The gene discussed is NCR3; the disease is antisynthetase syndrome.