TNF and injury: Inhibits T cell proliferation & suppresses expression of the T cell-derived proinflammatory cytokines IL-2, TNF-α & IFN-γ via NF-κB-mediated inhibition of mRNA expression (211).Attenuates LPS-induced acute lung injury by inhibiting NF-κB activation (229).Reduces progression of cerebral ischemia-reperfusion injury in rats by suppressing the activation of NF-κB, p65 & p38 MAPK (230).