FOXP3 and susceptibility to pneumonia measurement: For selected patients (n=3 in control; n=3 in ICI-pneumonia; n=2 in ICI-pneumonitis), along with chemokine/cytokine receptors, we also investigated expression of key transcription factors including T-bet (Th1), GATA3 (Th2), RoRγT (Th17), and FoxP3 (Treg) (Figure 3E; Supplementary Figure 3) (10).