Although CCR5 Delta32/Delta32 is present in about 1% of the general population (70), only one more documented case of HSCT from a CCR5 Delta32 homozygous donor, has been reported in a HIV patient; HIV viremia became undetectable but the patient died of his underlying lymphoma, thus hindering any evaluation of long-term post-transplant outcome of the HIV infection. Here, CCR5 is linked to HIV infectious disease.