AKT1 and breast carcinoma: A friedolanostane triterpenoid (methyl−3α,23−dihydroxy−17,14−friedolanstan−8,14,24−trien−26−oat) was isolated from Garcinia celebica L. and tested on MCF-7 breast cancer cell; the compound inhibited cell proliferation in a time- and dose-dependent manner by inhibiting the oncogenic protein AKT and increasing the expression of the poly (ADP-ribose) polymerase (PARP) protein thus promoting apoptosis and cell death (67).