ROCK1 and chronic obstructive pulmonary disease: Several studies have revealed a diverse range of functions of ROCK1 and 2 in the context of lung diseases (Htwe et al., 2017) and ROCK inhibitors have potential therapeutic applicability in lung diseases such as asthma, COPD and pulmonary fibrosis (Hallgren et al., 2012; Vigil et al., 2012; Htwe et al., 2017; dos Santos et al., 2018; Knipe et al., 2018).