SLC2A1 and early-onset autosomal dominant Alzheimer disease: Since aberrations in carbohydrate availability and transport are thought to be a major cause of severe illnesses, like GLUT1 deficiency syndrome, Alzheimer's disease or epilepsy (Kapogiannis and Mattson, 2011; Arsov et al., 2012; Hoffmann et al., 2013; Koepsell, 2020), it will be very interesting to unravel the regulatory mechanisms that can lead to a compensation of insufficient carbohydrate uptake.