Out of 19 morphological parameters assessed in the stroke perilesional and ipsilateral hemisphere regions (38 parameters), a significant change in 3838 measured IBA1+ parameters, 3438 GFAP+ parameters, 3238 NeuN+ parameters, 3138 FactorVIII+ parameters, and 2838 DCX+ parameters were observed in stroked vs. non-stroked animals. The gene discussed is AIF1; the disease is stroke disorder.