SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: Ion channelopathies like α1-sodium channel subunit (SCN1A) and sodium-activated potassium channel gene (KCNT1), typically associated with Dravet syndrome and sleep-related hypermotor epilepsy, respectively, can co-occur with histologically proven FCD (Barba et al., 2014; Rubboli et al., 2019).