Additionally, in a landmark study of paraneoplastic thrombocytosis in patients with epithelial ovarian cancer, Stone et al. [32] conducted parallel clinical and experimental analyses and found that advanced disease was associated with thrombocytosis, which was significantly correlated with the levels of IL-6 and thrombopoietin and associated with a significantly shorter progression-free and overall survival. Here, THPO is linked to ovarian carcinoma.