In addition, we combined the HRs of 14 studies using the Cox proportional hazard model for multivariate analysis of the survival data and found that Jab1 overexpression acts as an independent prognostic indicator for OS in human cancers (pooled HR 2.190, 95%CI: 1.853‐2.587) with low heterogeneity detected. This evidence concerns the gene COPS5 and cancer.