Patients who were involuntarily switched to IDeg (i.e., previous basal insulin was no longer covered by insurance; N = 43) reported significant improvements in HABS anxiety subscale score (P = 0.043), DDS emotional burden subscale score (P = 0.023), feelings of freedom and flexibility total score (P = 0.0039), and average number of hours of restful sleep (P = 0.0002; Table 2). The gene discussed is INS; the disease is Anxiety.