KLK3 and familial reactive perforating collagenosis: A number of parameters can contribute to the likelihood of a positive PET/CT in rPC, and these would ideally be controlled and directly comparable between cohorts: the prostate-specific antigen level (PSA) and clinical setting (post-radiotherapy or post-prostatectomy) were all identified as independent predictors of a positive PSMA-PET/CT [47].