AKT1 and cancer: Cai et al. [30] confirmed that EBV-miR-BART7-3p targets the human cancer suppressor gene PTEN in NPC cells, activates the PI3K/Akt/GSK-3β signaling axis and finally induces the high expression and intranuclear translocation of Snail and β-catenin to facilitate EMT (Fig. 2).